Climate change is occurring due to natural internal processes or external force and is defined as: “a change of climate which is attributed directly or indirectly to human activity that alters the composition of the global atmosphere and which is in addition to natural climate variability observed over comparable time periods.” It affects social and environmental determinants of health like –clean air, safe drinking water, sufficient food and secure shelter. Climate change may negatively affect human health through a number of ways, but the commonly experienced are increased frequency and intensity of heat waves, rise in heat related illnesses and deaths, increased precipitation, floods and droughts, costing lives directly. High temperature is known to increase the level of ‘ground level ozone’ and other ‘climate altering pollutants’ other than carbon dioxide, which further exacerbate cardio-respiratory and allergic diseases and certain cancers. Beside these, there is increase in transmission and spread of infectious diseases, changes in the distribution of waterborne, food borne and vector-borne diseases and effects on the risk of disasters and malnutrition. The United Nations Framework Convention on Climate Change (UNFCCC) came into force on 21st March 1994. Since then many steps were initiated to reduce the effect of climate change at meetings like “Rio Convention 1992”, Kyoto protocol 1997”, “Convention of Parties”, “Cancun Agreement 2010”,” Durban Platform 2011”,” Nationally Determined Contributions” (NDCs) at Conference of Parties 21”, Initiatives undertaken by India are: a) Identification of Ministry of Environment, Forest & Climate Change (MOEF&CC) as nodal ministry; b) Formulation of National Environmental Policy 2006; c) Formulation of Prime Minister’s Council on Climate Change for matters related to Climate Change. MoEFCC has developed National Action Plan on Climate Change with eight missions. Later on four new missions (including Health Mission) were identified. As a follow-up action, MoHFW constituted a National Expert Group on Climate Change & Health (NEGCCH) under the chairmanship of Dr Vishwa Mohan Katoch, Former Secretary (Health Research), Government of India and DG (ICMR) to prepare action plan, recommend strategies for indicators, mitigation, capacity building etc. The Health Mission aims to reduce climate sensitive illnesses through integration with other missions under NAPCC as well as through programmes run by various ministries, The vision of NAPCCHH is: To strengthen health of citizens of India against climate sensitive illness, especially among the vulnerable like children, women and marginalized population. With a goal to reduce morbidity, mortality, injuries and health vulnerability to climate variability and extreme weathers.