Dr. Rajan N. Khobragade is an accomplished Indian Administrative Service (IAS) officer of the 1993 batch, currently serving as the Additional Chief Secretary (ACS) in the Department of Health and Family Welfare, Government of Kerala. In addition to this key role, he holds full additional charges of the Departments of Ayush and Cultural Affairs, which encompass the Archaeology, Archives, and Museums sectors. With a distinguished career spanning various leadership positions, Dr. Khobragade previously served as the Chairman and Managing Director of Kerala State Electricity Board Limited and as the Commissioner of Commercial Taxes, Government of Kerala. During his tenure as Commissioner of Commercial Taxes, he was instrumental in the successful implementation of the Goods and Services Tax (GST) regime in Kerala.

A medical graduate by training, Dr. Khobragade has extensive experience in the health sector, having held several pivotal positions. Notably, he served as the Chief of the National Technical Support Unit of the National AIDS Control Organisation (NACO) and as the Project Director of the Kerala State AIDS Control Society (KSACS). As Project Director of KSACS, Dr. Khobragade spearheaded innovative interventions to combat AIDS-related stigma, notably by engaging local self-governments, particularly Panchayats, in awareness and de-stigmatization initiatives. This community-centric approach significantly strengthened Kerala's response to the HIV/AIDS program. Dr. Khobragade also served as the Principal Secretary of the Health and Family Welfare Department, where he played a critical role in formulating and leading Kerala's strategic response to the COVID-19 pandemic. Under his leadership, the department's efforts were widely acclaimed both nationally and internationally for their effectiveness, resilience, and comprehensive public health strategies.Dr. Rajan N. Khobragade has been instrumental in pioneering Kerala’s efforts to combat Nipah and other zoonotic diseases, while leading the formulation of a comprehensive One Health framework for the State. This framework is designed to effectively address existing, re-emerging, and emerging health threats, including zoonotic and plant-related diseases as well as antimicrobial resistance (AMR).The establishment of the Centre for One Health–Kerala and the development of the “Kerala Model of One Health” have created an integrated platform for coordinated surveillance, preparedness, and response across human, animal, and environmental health sectors, serving as a reference framework for other states and agencies seeking to design and implement their own One Health initiatives.